Genetic toxicology of thallium: a review
WebSep 12, 2012 · This review summarizes the current knowledge about the general toxicity of thallium (Tl) and its environmental sources, with special emphasis placed on its potential mutagenic, genotoxic, and cytotoxic effects on both eukaryotic and prokaryotic cells. Web[GENETIC CAUSES OF ABNORMAL DRUG EFFECTS] Internist (Berl). 1964 Jun;5:224-32. ... No abstract available. Publication types Review MeSH terms Drug Hypersensitivity* Drug Therapy* Drug Tolerance* Genetics, Medical* ... Toxicology* ...
Genetic toxicology of thallium: a review
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WebJan 1, 2016 · Thallium (Tl) is a highly toxic heavy metal widely present in the environment. Case reports have suggested that maternal exposure to high levels of Tl during pregnancy is associated with low birth weight (LBW), but epidemiological data are limited. Objectives WebMar 12, 2013 · • With 15 years of industrial experience in regulatory toxicology and nonclinical development of biologics, small molecules, mRNA therapeutics/vaccines, and RNAi genetic medicines. A ...
WebThallium has severe toxicity. Although its acute biological effects have been widely investigated and are well known, its biological effects on human health and in cell … WebJan 1, 2024 · Thallium has no known biological function and has been the least studied of the toxic metals including lead, mercury, and cadmium. Thallium salts were introduced …
WebApr 22, 2024 · Rodríguez-Mercado JJ, Altamirano-Lozano MA (2012) Genetic toxicology of thallium: a review. Drug Chem Toxicol 36(3):369–383 ... Xu H, Luo Y, Wang P, Zhu J, Yang Z, Liu Z (2024) Removal of thallium in water/wastewater: a review. Water Res 165:114981. Article CAS Google Scholar Xu X, Cao X, Zhao L, Wang H, Yu H, Gao B … WebThese studies, which are designed to identify genotoxic hazard, include: • A test for gene mutation in bacteria; • An in vitro assessment of chromosomal damage using mammalian cells or an in vitro...
WebApr 27, 2024 · Thallium (Tl +) is a heavy metal that causes toxicity in several organs, including the brain. Its cytotoxic profile, combined with its affinity for tumor cells when used as a radioligand for labeling these cells, suggests its potential use as antitumor therapy.
WebThis review summarizes the current knowledge about the general toxicity of thallium (Tl) and its environmental sources, with special emphasis placed on its potential mutagenic, genotoxic, and cytotoxic effects on both eukaryotic and prokaryotic cells. dlt1 cleaning cartridgeWebSep 12, 2012 · Europe PMC is an archive of life sciences journal literature. crbsi prevention bundleWebThis review summarizes the current knowledge about the general toxicity of thallium (Tl) and its environmental sources, with special emphasis placed on its potential mutagenic, … dlsz senior high schoolWebSep 10, 2024 · Genetic toxicology of thallium: a review. Drug Chem Toxicol. 2013;36:369–83. CrossRef PubMed Google Scholar Saddique A, Peterson CD. Thallium poisoning: a review. Vet Hum Toxicol. … crbs scotlandWebThis review summarizes the current knowledge about the general toxicity of thallium (Tl) and its environmental sources, with special emphasis placed on its potential … dlt104 checks staplesWebSep 20, 2008 · Thallium is excreted both in animal and men through kidney, intestine and in small parts via hair and milk. The concentration of thallium in urine and hair is taken as an indicator of internal exposure; permissible exposure limit is O.1 mgTl/m3. ... Genetic toxicology of thallium: a review. Juan José Rodríguez-Mercado et al. Drug and … crb slewing bearingWebNov 26, 2024 · In the current review, we focus on the rare earth elements, thallium, and tellurium. It has been documented that they can pass through the gastrointestinal tract and accumulate in the human body causing short- or long-term structural or functional alterations that can eventually lead to a toxic effect. 1.1 Rare Earth Elements crbs s/a cnpj