WebBackground: The protein high-mobility group AT-hook 1 (HMGA1) has been demonstrated that modulated cellular proliferation, invasion, and apoptosis with a poor prognosis in miscellaneous carcinomas. However, the mechanism of circumstantial carcinogenesis and association with the immune microenvironment of HMGA1 in hepatocellular carcinoma … WebBackground: The protein high-mobility group AT-hook 1 (HMGA1) has been demonstrated that modulated cellular proliferation, invasion, and apoptosis with a poor prognosis in …
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WebName high mobility group AT-hook 1 Synonyms Hmga1a, Hmga1b, Hmgi, Hmgiy, HMG-I (Y), HMGI (Y), HMGY Feature Type protein coding gene IDs MGI:96160 NCBI Gene: 15361 Alliance gene page Transcription Start Sites 25 TSS Location & Maps more Sequence Map Chr17:27775548-27782646 bp, + strand From NCBI annotation of GRCm39 Genetic Map WebApr 29, 2024 · 1. Introduction. High mobility group AT-hook 2 (HMGA2) belongs to the HMGA family of small, non-histone chromatin-associated proteins . This protein is encoded by the HMGA2 gene localized to human chromosome 12 at band q14.3 , comprising five exons dispersed over a genomic region of ≥140 kb. inclusion\u0027s 6g
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WebHigh Mobility Group A1 (HMGA1) proteins interact with p53 and inhibit its apoptotic activity. Pierantoni, G.M., Rinaldo, C., Esposito, F., Mottolese, M., Soddu, S., Fusco, A. Cell Death Differ. (2006) [ Pubmed] Rice HMGB1 protein recognizes DNA structures and bends DNA efficiently. Wu, Q., Zhang, W., Pwee, K.H., Kumar, P.P. Arch. Biochem. WebDec 11, 2024 · The present study investigated if c‑MYC and high mobility group AT‑hook 2 (HMGA2) expression was associated with prognosis of patients with pancreatic ductal adenocarcinoma (PDAC). A total of 102 patients undergoing surgery for PDAC were retrospectively reviewed. Immunohistochemistry was used to detect c‑MYC and HMGA2 … WebHigh mobility group AT-hook 1 (HMGA1) proteins are architectural transcription factors that are overexpressed by pancreatic adenocarcinomas. The authors hypothesized that tumor HMGA1 status represents a novel prognostic marker in pancreatic adenocarcinoma. They also tested the hypothesis that HMGA1 promotes anchorage-independent cellular ... inclusion\u0027s 68