WebA convenient, high-quality mix for moist, flavorful cake with excellent volume and shelf life. Perfect for layer cakes, celebration cakes and cupcakes. Add oil and water Make … More than 30 different precursor proteins may form amyloid, but only two types of amyloidosis commonly affect the heart: immunoglobulin light chain amyloidosis (AL) due to a plasma cell dyscrasia, and transthyretin amyloidosis (ATTR) due to misfolding of transthyretin (prealbumin), which transports … See more There are two types of ATTR amyloidosis: ATTRv, the hereditary form caused by pathogenic mutations of the transthyretin gene, and ATTRwt, … See more Treatment options for ATTR amyloidosis are rapidly expanding. Diflunisal is a transthyretin stabilizer shown to slow progression of neuropathy in patients with ATTRv amyloidosis. … See more Results of the trial, published in the Sept. 13, 2024, New England Journal of Medicine, are very encouraging. In the analysis of primary endpoints, all-cause mortality (29.5 … See more This observation led to the design and implementation of the Transthyretin Amyloidosis Cardiomyopathy Clinical Trial (ATTR-ACT), a phase 3, multicenter parallel-design, … See more

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